Mucin-16

MUC16
Identifiers
Aliases	MUC16, CA125, mucin 16, cell surface associated
External IDs	OMIM: 606154; HomoloGene: 133291; GeneCards: MUC16; OMA:MUC16 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	8,981,342 bp
RNA expression pattern
	Top expressed in
	nasal epithelium; ; epithelium of bronchus; ; olfactory zone of nasal mucosa; ; bronchial epithelial cell; ; mucosa of paranasal sinus; ; palpebral conjunctiva; ; trachea; ; epithelium of nasopharynx; ; right uterine tube; ; minor salivary glands;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	Golgi lumen; integral component of membrane; extracellular region; vesicle; extracellular exosome; membrane; extrinsic component of membrane; extracellular space; plasma membrane;
Biological process	cell adhesion; O-glycan processing; stimulatory C-type lectin receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	94025
	n/a
	ENSG00000181143
	n/a
	Q8WXI7
	n/a
	NM_024690; NM_001401501
	n/a
	NP_078966
	n/a
	Wikidata
View/Edit Human

Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins. MUC-16 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers, most notably ovarian cancer, or other conditions that are benign.