Central chemoreceptor

Central chemoreceptors are chemoreceptors beneath the ventral surface of the medulla oblongata which are highly sensitive to pH changes of nearby cerebrospinal fluid (CSF). The functional significance of the receptors is indirect monitoring of blood levels of CO2, thus providing an important parameter for the regulation of ventilation to the nearby respiratory center. Central chemoreceptors are the primary generator of regulatory feedback information for respiration while blood gas levels are around normal.

Peripheral chemoreceptors meanwhile also directly monitor blood O2.

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