Etorphine

Etorphine
Clinical data
AHFS/Drugs.com	International Drug Names
ATCvet code	QN02AE90 (WHO) ;
Legal status
Legal status	AU: S9 (Prohibited substance); BR: Class F1 (Prohibited narcotics); CA: Schedule I; DE: Anlage III (Special prescription form required); UK: Class A; US: Schedule I and Schedule II; UN: Narcotic Schedules I and IV; EU: List I (Netherlands);
Identifiers
	IUPAC name (5α,6β,14β,18R)-18-[(2R)-2-Hydroxy-2-pentanyl]-6-methoxy-17-methyl-7,8-didehydro-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol;
CAS Number	14521-96-1 ;
PubChem CID	644209;
IUPHAR/BPS	1625;
DrugBank	DB01497 ;
ChemSpider	559231 ;
UNII	42M2Y6NU9O;
KEGG	D07937 ;
ChEBI	CHEBI:4912 ;
ChEMBL	ChEMBL140050;
CompTox Dashboard (EPA)	DTXSID40878669 DTXSID40878667, DTXSID40878669 ;
ECHA InfoCard	100.035.017
Chemical and physical data
Formula	C25H33NO4
Molar mass	411.542 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@](CCC)(O)[C@H]1C[C@]23C=C[C@]1(OC)[C@@H]4Oc5c(O)ccc6C[C@H]2N(C)CC[C@]43c65;
	InChI InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3/t17-,18-,21-,22-,23-,24+,25-/m1/s1 ; Key:CAHCBJPUTCKATP-FAWZKKEFSA-N ;
	(what is this?) (verify)

Etorphine (M99) is a semi-synthetic opioid possessing an analgesic potency approximately 1,000–3,000 times that of morphine. It was first prepared in 1960 from oripavine, which does not generally occur in opium poppy extract but rather the related plants Papaver orientale and Papaver bracteatum. It was reproduced in 1963 by a research group at MacFarlan Smith in Edinburgh, led by Kenneth Bentley. It can be produced from thebaine.