Fibromyalgia

Fibromyalgia
Other namesFibromyalgia syndrome
Pronunciation
  • /ˌfbrmˈælə/
SpecialtyRheumatology, neurology
SymptomsWidespread pain, fatigue, sleep problems
Usual onsetEarly–Middle age
DurationLong term
CausesUncertain
Diagnostic methodBased on symptoms after ruling out other potential causes
Differential diagnosisAnemia, autoimmune disorders (such as ankylosing spondylitis, polymyalgia rheumatica, rheumatoid arthritis, scleroderma, or multiple sclerosis), Lyme disease, osteoarthritis, thyroid disease
TreatmentSufficient sleep and exercise
MedicationDuloxetine, milnacipran, pregabalin
PrognosisNormal life expectancy
Frequency2%

Fibromyalgia (FM) is a syndrome with symptoms of widespread chronic pain, accompanied by fatigue, sleep disturbance including awakening unrefreshed, and cognitive symptoms. Other symptoms can include headaches, lower abdominal pain or cramps, and depression. People with fibromyalgia can also experience insomnia and extreme sensitivity. The causes of fibromyalgia are unknown, with several pathophysiologies proposed.

Fibromyalgia is estimated to affect 2 to 4% of the population. Women are affected at a higher rate than men. Rates appear similar across areas of the world and among varied cultures. Fibromyalgia was first recognised in the 1950s, and defined in 1990, with updated criteria in 2011, 2016, and 2019.

The treatment of fibromyalgia is symptomatic and multidisciplinary. Aerobic and strengthening exercise are recommended. Duloxetine, milnacipran, and pregabalin can give short-term pain relief to some FM people. Symptoms of fibromyalgia persist long term in most patients.

Fibromyalgia is associated with a significant economic and social burden, and it can cause substantial functional impairment amongst people with the condition. People with fibromyalgia can be subjected to significant stigma and doubt about the legitimacy of their symptoms, including in the healthcare system.