| MAOA |
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| Available structures |
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| PDB | Ortholog search: PDBe RCSB |
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| Identifiers |
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| Aliases | MAOA, MAO-A, monoamine oxidase A, BRNRS |
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| External IDs | OMIM: 309850; MGI: 96915; HomoloGene: 203; GeneCards: MAOA; OMA:MAOA - orthologs |
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| Gene location (Mouse) |
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| | Chr. | X chromosome (mouse) |
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| | Band | X A1.2|X 11.78 cM | Start | 16,485,937 bp |
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| End | 16,554,057 bp |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - mucosa of ileum
- mucosa of colon
- mucosa of sigmoid colon
- right lung
- jejunal mucosa
- duodenum
- rectum
- parotid gland
- gastric mucosa
- mucosa of transverse colon
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| | Top expressed in | - left colon
- superior cervical ganglion
- jejunum
- duodenum
- intestinal villus
- Ileal epithelium
- stroma of bone marrow
- endothelial cell of lymphatic vessel
- crypt of lieberkuhn of small intestine
- Paneth cell
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| | More reference expression data |
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| BioGPS | |
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| Gene ontology |
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| Molecular function | | | Cellular component | | | Biological process | | | Sources:Amigo / QuickGO |
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| Wikidata |
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Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as norepinephrine, serotonin and tyramine. A mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
