Serine

Serine
Skeletal formula of L-serine
L-serine zwitterion
Ball-and-stick model
Space-filling model
Names
IUPAC name
Serine
Systematic IUPAC name
2-Amino-3-hydroxypropanoic acid
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.000.250
EC Number
  • L: 206-130-6
KEGG
PubChem CID
UNII
InChI
  • InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1 Y
    Key: MTCFGRXMJLQNBG-REOHCLBHSA-N Y
  • D/L: Key: MTCFGRXMJLQNBG-UHFFFAOYSA-N
  • D: Key: MTCFGRXMJLQNBG-UWTATZPHSA-N
SMILES
  • L: C([C@@H](C(=O)O)N)O
  • D/L Zwitterion: C([C@@H](C(=O)[O-])[NH3+])O
Properties
Chemical formula
C3H7NO3
Molar mass 105.093 g·mol−1
Appearance white crystals or powder
Density 1.603 g/cm3 (22 °C)
Melting point 246 °C (475 °F; 519 K) decomposes
Solubility in water
soluble
Acidity (pKa) 2.21 (carboxyl), 9.15 (amino)
Supplementary data page
Serine (data page)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Serine /ˈsɪəriːn/ (symbol Ser or S) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+
3
form under biological conditions), a carboxyl group (which is in the deprotonated −COO
form under biological conditions), and a side chain consisting of a hydroxymethyl group, classifying it as a polar amino acid. It can be synthesized in the human body under normal physiological circumstances, making it a nonessential amino acid. It is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC.