VCAM-1

VCAM1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1IJ9, 1VCA, 1VSC
Identifiers
Aliases	VCAM1, CD106, INCAM-100, vascular cell adhesion molecule 1
External IDs	OMIM: 192225; MGI: 98926; HomoloGene: 838; GeneCards: VCAM1; OMA:VCAM1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	100,739,045 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	115,923,337 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; trabecular bone; ; parietal pleura; ; tendon of biceps brachii; ; vena cava; ; spleen; ; glomerulus; ; metanephric glomerulus; ; synovial joint; ; kidney tubule;
	Top expressed in
	stroma of bone marrow; ; spleen; ; dermis; ; Epithelium of choroid plexus; ; tibiofemoral joint; ; choroid plexus of fourth ventricle; ; left lung lobe; ; atrium; ; human fetus; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	primary amine oxidase activity; integrin binding; cell adhesion molecule binding;
Cellular component	integral component of membrane; Golgi apparatus; alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex; membrane; filopodium; plasma membrane; apical part of cell; microvillus; cell surface; early endosome; endoplasmic reticulum; podosome; sarcolemma; extracellular exosome; external side of plasma membrane; extracellular space; integral component of plasma membrane;
Biological process	leukocyte cell-cell adhesion; response to ionizing radiation; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; response to hypoxia; response to nutrient; interferon-gamma-mediated signaling pathway; cellular response to tumor necrosis factor; response to nicotine; ageing; response to zinc ion; extracellular matrix organization; amine metabolic process; response to lipopolysaccharide; cell adhesion; acute inflammatory response; positive regulation of T cell proliferation; membrane to membrane docking; regulation of immune response; leukocyte tethering or rolling; cell chemotaxis; B cell differentiation; cellular response to vascular endothelial growth factor stimulus; cell-matrix adhesion; viral process; response to ethanol; calcium-mediated signaling using intracellular calcium source; chronic inflammatory response; cell-cell adhesion; cytokine-mediated signaling pathway; heterotypic cell-cell adhesion; innervation; cardiac neuron differentiation; cell-cell adhesion in response to extracellular stimulus; cellular response to amyloid-beta;
	Sources:Amigo / QuickGO
Orthologs
	7412
	22329
	ENSG00000162692
	ENSMUSG00000027962
	P19320
	P29533
	NM_080682; NM_001078; NM_001199834
	NM_011693
	NP_001069; NP_001186763; NP_542413
	NP_035823
	Wikidata
View/Edit Human	View/Edit Mouse

Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that in humans is encoded by the VCAM1 gene. VCAM-1 functions as a cell adhesion molecule.